Assessment of measles incidence, measles-related complications and hospitalisations during an outbreak in a southern Italian region

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• 作者：Marta Luisa Ciofi degli Atti ; Antonietta Filia ; Marco Massari ; Renato Pizzuti ; Loredana Nicoletti ; Angelo D’ ; Argenzio ; Enrico de Campora ; Antonella Marchi ; Assunta Lombardo ; Stefania Salmaso and
• 关键词：Measles ; Epidemic ; Surveillance ; Vaccination
• 刊名：Vaccine
• 出版年：2006
• 出版时间：27 February 2006
• 年：2006
• 卷：24
• 期：9
• 页码：1332-1338
• 全文大小：124 K

文摘

A large measles epidemic occurred in 2002 in Campania, a region of southern Italy with inadequate vaccination coverage. We evaluated the burden of the outbreak in children <15 years of age using different data sources. The measles standardized incidence rate was 5757/100,000, corresponding to 63,368 estimated cases (95 % CI: 59,544–67,373). Measles virus strains were identified as belonging to the D7 genotype. The estimated complication rate was 7.6 % . A total of 972 measles hospitalisations were detected, giving a hospitalisation rate of 88.3/100,000. Three deaths occurred. These results show that measles can still represent a serious health threat even in industrialized countries.