Differential effect of the 17尾-aminoestrogens prolame, butolame and pentolame in anxiety and depression models in rats

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Differential effect of the 17尾-aminoestrogens prolame, butolame and pentolame in anxiety and depression models in rats

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作者：C. Lemini^a ; E. Garcí ; a-Albor^b ; B. Cruz-Ló ; pez^b ; G. Matamoros-Trejo^c ; L. Martí ; nez-Mota^b ; ^{lucia@imp.edu.mx" class="auth_mail" title="E-mail the corresponding author}
关键词：17尾-Aminoestrogens ; Animal models ; Anxiety ; Depression ; Hormone replacement therapy
刊名：Progress in Neuropsychopharmacology & Biological Psychiatry
出版年：2016
出版时间：4 January 2016
年：2016
卷：64
期：Complete
页码：102-108
全文大小：622 K

文摘

•: 17尾-Aminoestrogens (AEs) at high doses induce anticoagulant effect in different models.
•: Pentolame and butolame exhibited specific anxiolytic-like activity.
•: Prolame as E₂ produced antidepressant-like and anxiolytic-like effects.
•: AEs could be used as restitution therapy with advantages over conventional ones.

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