Rooibos (Aspalathus linearis) facilitates an anti-inflammatory state, modulating IL-6 and IL-10 while not inhibiting the acute glucocorticoid response to a mild novel stressor in vivo

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• 作者：Carine Smith^a ; Amanda C. Swart^b ; ^{acswart@sun.ac.za}
• 关键词：IL-10 and IL-6 cytokines ; Inflammation ; Adrenal cortisol and corticosterone ; Stress ; Flavonoid glucoside polyphenols
• 刊名：Journal of Functional Foods
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：27
• 期：Complete
• 页码：42-54
• 全文大小：981 K
• 卷排序：27

文摘

Rooibos consumption is associated with an anti-inflammatory outcome. Rooibos decreased IL-6 and increased IL-10 levels in vivo. Rooibos limits glucocorticoid synthesis in H295R cells independent of IL-6 and IL-10. Rooibos inhibition of basal GC biosynthesis does not prevent an acute stress response. Data underline Rooibos as a functional food in reducing risk for chronic disease.