Stereoselective total synthesis of cryptomoscatone D1 and (5R,7S)-kurzilactone via ring closing metathesis

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• 作者：Ramesh Perla ; ^{perlaramesh@yahoo.co.in" class="auth_mail" title="E-mail the corresponding author} ; Raju Atla ; Paramesh Jangili ; Ramisetti Anjibabu
• 关键词：Styryl lactones ; Mukaiyama aldol reaction ; Diastereoselective reduction ; Brown&rsquo ; s allylation ; Ring closing metathesis
• 刊名：Tetrahedron Letters
• 出版年：2016
• 出版时间：9 March 2016
• 年：2016
• 卷：57
• 期：10
• 页码：1087-1089
• 全文大小：601 K

文摘

Total synthesis of styryl lactone natural products cryptomoscatone D1, D2, and (5R,7S)-kurzilactone has been accomplished in good yield from commercial available trans-cinnamaldehyde. The key steps involved in these syntheses are Mukaiyama aldol reaction, diastereoselective reduction, Brown’s allylation, and ring closing metathesis.