Role of D2 dopamine receptors of the ventral pallidum in inhibitory avoidance learning

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• 作者：Lá ; szló ; Lé ; ná ; rd^a ; ^b ; ^{laszlo.lenard@aok.pte.hu} ; Tamá ; s Ollmann^a ; Kristó ; f Lá ; szló ; ^a ; Anita Ková ; cs^a ; Rita Gá ; losi^a ; Veronika Ká ; llai^a ; Tó ; th Attila^a ; Erika Kertes^a ; Olga Zagoracz^a ; Zoltá ; n Kará ; di^a ; ^b ; Lá ; szló ; Pé ; czely^a
• 关键词：Ventral pallidum ; Inhibitory avoidance learning ; Memory consolidation ; D2 dopamine receptors ; Quinpirole ; Sulpiride
• 刊名：Behavioural Brain Research
• 出版年：2017
• 出版时间：15 March 2017
• 年：2017
• 卷：321
• 期：Complete
• 页码：99-105
• 全文大小：1297 K
• 卷排序：321

文摘

D2 dopamine receptor agonist quinpirole was microinjected into the ventral pallidum. The 0.1 μg agonist enhances memory consolidation in inhibitory avoidance learning. The same dose increases memory retention even 2 weeks after conditioning. D2 dopamine receptor antagonist sulpiride pretreatment eliminates agonist’s effect. The ventral pallidal D2 dopamine receptor activation enhances learning processes.