The role of autophagy in modulation of neuroinflammation in microglia

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The role of autophagy in modulation of neuroinflammation in microglia

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作者：P. Su^a ; J. Zhang^a ; D. Wang^a ; F. Zhao^a ; Z. Cao^a ; M. Aschner^b ; W. Luo^a ; ^{luowenj@fmmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：3-MA ; 3-methyladenine ; ACAT1 ; Acyl-CoA ; cholesterol acyltransferase 1 ; AD ; Alzheimer&rsquo ; s disease ; Atg ; autophagy-related protein ; AVs ; autophagic vesicles ; Aβ ; amyloid beta ; BCAS ; bilateral common carotid artery stenosis ; CB2R ; cannabinoid receptor 2 ; CMA ; chaperone-mediated autophagy ; CNS ; central nervous system ; ERK ; extracellular signal-regulated kinase ; ES ; electric stimulation ; HANDs ; HIV-1-associated neurocognitive disorders ; HIF-1α ; hypoxia-inducible factor 1 alpha ; ICH ; intracerebral
刊名：Neuroscience
出版年：2016
出版时间：5 April 2016
年：2016
卷：319
期：Complete
页码：155-167
全文大小：544 K

文摘

•: Microglial autophagy can influence the inflammatory response and survival of microglia.
•: Microglial autophagy may be pro-inflammatory or anti- inflammatory.
•: Many mechanisms involved in mediating the process of microglial autophagy.

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