Clustering of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and infective dermatitis associated with HTLV-1 (IDH) in Salvador, Bahia, Brazil

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• 作者：Jos¨¦ Lucas Sena da Silva ; Janeusa Rita L. Primo ; Maria de F¨¢tima S.P. de Oliveira ; Everton da Silva Batista ; Ot¨¢vio Moreno-Carvalho ; Lourdes Farr¨¦ ; Achil¨¦a L. Bittencourt
• 关键词：HTLV-1 infection ; Clustering of HTLV-1-associated diseases ; HTLV-1 associated myelopathy/tropical spastic paraparesis ; Infective dermatitis associated with HTLV-1 ; HTLV-1 vertical transmission
• 刊名：Journal of Clinical Virology
• 出版年：2013
• 出版时间：October, 2013
• 年：2013
• 卷：58
• 期：2
• 页码：482-485
• 全文大小：706 K

文摘

Fifteen families with clustering of infective dermatitis associated with HTLV-1 (IDH) and/or HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) were observed among 28 families of IDH index cases, 93 % of them occurring in two generations. With the exception of two mothers of children with IDH, all the mothers with HAM/TSP had at least one child with HAM/TSP. This is the first report of such clustering involving many families.