Presence of T-275A and C-2152T Polymorphisms of the Promoter Region of Uridine Diphosphate-Glucuronosyltransferase 1A9 Increases Mortality From Digestive Tumors: Results After 10 Years of Follow-up in a Renal Transplant Population

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• 作者：N. Calvo ; A. Shabaka ; B. Rodriguez Cubillo ; V. Ló ; pez de la Manzanara ; I. Pé ; rez-Flores ; M.A. Moreno de la Higuera ; J. Bautista ; A.I. Sá ; nchez-Fructuoso
• 刊名：Transplantation Proceedings
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：48
• 期：9
• 页码：2947-2949
• 全文大小：243 K
• 卷排序：48

文摘

Renal transplant recipients who carry T-275A and C-2152T SNPs of the UGT1A9 gene promoter region show a greater incidence of death from cancer. There is a higher accumulative incidence of gastrointestinal tumors in region T-275A and C-2152T polymorphism carriers. There is a relative high incidence of T-275A and C-2152T in the renal transplant population.