Arylalkylamine N-acetyltransferase 1 gene (TcAANAT1) is required for cuticle morphology and pigmentation of the adult red flour beetle, Tribolium castaneum

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• 作者：Mi Young Noh^a ; Bonwoo Koo^a ; Karl J. Kramer^b ; Subbaratnam Muthukrishnan^b ; Yasuyuki Arakane^a ; ^{arakane@chonnam.ac.kr}
• 关键词：N-acetyltransferase ; Tribolium castaneum ; Cuticle pigmentation ; Elytron ; RNA interference (RNAi) ; Trabeculae
• 刊名：Insect Biochemistry and Molecular Biology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：79
• 期：Complete
• 页码：119-129
• 全文大小：2750 K
• 卷排序：79

文摘

rTcAANAT1 protein acts on a wide range of substrates such as dopamine, norepinephrine, tryptamine, tyramine and octopamine. The Km values of rTcAANAT1 for monoamine substrates are similar except for a lower affinity for tyramine. High transcript levels of TcAANAT1 are detected right after pupation and right before adult eclosion. RNAi-based functional study reveals that TcAANAT1 gene is required for morphology and pigmentation of adult cuticle.