hESC model to study neurodevelopmental regulation of MECP2 3′ UTR use and function

MECP2 long 3′ UTR transcript is destabilized by PUM1 and miRNAs in hESCs

MECP2 translation is repressed by TIA1 in hESCs and enhanced by HuC in neurons

Combinatorial circuitry regulates MECP2 3′ UTR stability and MECP2 protein levels