Characterization of a specific monoclonal antibody against immunoglobulin light kappa/L1 chain in olive flounder (Paralichthys olivaceus)

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• 作者：Young Kyu Kim^a ; Jung Seok Lee^a ; Jae Wook Jung^a ; Jun-ichi Hikima^b ; Maki Ohtani^c ; Ho Bin Jang^a ; Seong Won Nho^a ; In Seok Cha^a ; Seong Bin Park^a ; Jeong Ho Lee^e ; Takashi Aoki^d ; Tae Sung Jung^a ; ^{jungts@gnu.ac.kr}
• 关键词：Immunoglobulin (Ig) ; Igκ-a ; Monoclonal antibodies (mAbs) ; Olive flounder
• 刊名：Fish & Shellfish Immunology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：60
• 期：Complete
• 页码：88-96
• 全文大小：1885 K
• 卷排序：60

文摘

Olive flounder has three isotypes of IgL, two of κ, and one of σ. M7C3-4 produced against serum immunoglobulins of olive flounder specifically recognizes Igκ-a isotype. Igκ-a+ B cells are more abundant in organs than in peripheral blood.