Intratracheal therapy with autologous bone marrow-derived mononuclear cells reduces airway inflammation in horses with recurrent airway obstruction

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Intratracheal therapy with autologous bone marrow-derived mononuclear cells reduces airway inflammation in horses with recurrent airway obstruction

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作者：Fernanda C.M. Barussi^a ; ¹ ; Fernanda Z. Bastos^a ; ¹ ; Lidiane M.B. Leite^b ; Felipe Y.I. Fragoso^b ; Alexandra C. Senegaglia^b ; Paulo R.S. Brofman^b ; Anita Nishiyama^c ; Clá ; udia T. Pimpã ; o^a ; Pedro V. Michelotto Jr.^a ; ^{p.michelotto@pucpr.br" class="auth_mail" title="E-mail the corresponding author}
关键词：Bronchoalveolar lavage ; Heaves ; Horses ; Interleukins ; Neutrophils ; Pulmonary inflammation
刊名：Respiratory Physiology & Neurobiology
出版年：2016
出版时间：October 2016
年：2016
卷：232
期：Complete
页码：35-42
全文大小：820 K

文摘

•: The cell therapy reduced the number of neutrophils in the BALF.
•: The cell therapy increased the number of macrophages in the BALF.
•: The cell therapy improved the clinical parameters of RAO horses.
•: The cell therapy increased the level of the anti-inflammatory interleukin-10.
•: Instillation of BMMCs can be a new treatment for horses with RAO.

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