A Molecular Titration System Coordinates Ribosomal Protein Gene Transcription with Ribosomal RNA Synthesis

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A Molecular Titration System Coordinates Ribosomal Protein Gene Transcription with Ribosomal RNA Synthesis

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作者：Benjamin Albert<sup>1sup> ; Britta Knight<sup>1sup> ; Jason Merwin<sup>1sup> ; Victoria Martin<sup>1sup> ; Diana Ottoz<sup>1sup> ; Yvonne Gloor<sup>1sup> ; Maria Jessica Bruzzone<sup>1sup> ; Adam Rudner<sup>2sup><sup> ; sup><sup>3sup> ; David Shore<sup>1sup><sup> ; sup><sup>4sup><sup> ; sup><sup>david.shore@unige.ch" class="auth_mail" title="E-mail the corresponding authorsup>
关键词：transcription ; ribosomal protein gene ; ribosomal RNA ; Utp22 ; Ifh1 ; CURI complex ; Saccharomyces cerevisiae ; transcription factor titration
刊名：Molecular Cell
出版年：2016
出版时间：17 November 2016
年：2016
卷：64
期：4
页码：720-733
全文大小：2370 K

文摘

ss="label">•: Ifh1-Utp22 interaction coordinates RPG and rRNA transcription
ss="label">•: Sch9 regulates Ifh1 release at a short timescale after nutrient stress
ss="label">•: Utp22 is required for stable release of Ifh1 following TORC1 inhibition
ss="label">•: Utp22 couples RNAPI activity to RPG transcription independently of TORC1

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