Nucleo-mitochondrial interaction of yeast in response to cadmium sulfide quantum dot exposure

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• 作者：Francesco Pasquali^a ; Caterina Agrimonti^a ; Luca Pagano^a ; ^b ; ^c ; Andrea Zappettini^d ; Marco Villani^d ; Marta Marmiroli^a ; Jason C. White^c ; Nelson Marmiroli^a ; ^e ; ^{nelson.marmiroli@unipr.it}
• 关键词：CdS quantum dots ; Saccharomyces cerevisiae ; Pathological mitochondria ; Oxidative stress
• 刊名：Journal of Hazardous Materials
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：324
• 期：part_PB
• 页码：744-752
• 全文大小：1882 K
• 卷排序：324

文摘

CdS QDs induce oxidative stress in yeast. CdS QDs disrupt mitochondrial membrane potentials and morphology. CdS QDs do not affect mtDNA content. CdS QDs modify the expression of genes involved in mitochondrial organization and function. Deletion of some of these genes induces either tolerant or sensitive phenotypes to CdS QDs.