RA showed an aggregation behavior (c.m.c. of 35 μM at pH 8 and 25 °C) which could be modified by the presence of CD.
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The RA/CD complexes presented a 1:1 stoichiometry and the KF was dependent on pH, temperature and type of CD.
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The pKa calculated for RA was 4.31.
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Molecular docking provided further insights about the interactions in the complexes.
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