Reduction of methicillin-resistant Staphylococcus aureus infection in long-term care is possible while maintaining patient socialization: A prospective randomized clinical trial

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• 作者：Lance R. Peterson ; MD^a ; ^b ; ^c ; ^d ; ^e ; ^{lance1@uchicago.edu} ; Susan Boehm ; RN^d ; Jennifer L. Beaumont ; MS^f ; Parul A. Patel ; MT^d ; Donna M. Schora ; MT^d ; Kari E. Peterson ; MPH^d ; Deborah Burdsall ; RN^g ; Carolyn Hines ; RN^e ; Maureen Fausone ; BA^d ; Ari Robicsek ; MD^a ; ^c ; ^e ; Becky A. Smith ; MD^a ; ^c ; ^e
• 关键词：Long-term care facility (LTCF) ; methicillin-resistant Staphylococcus aureus (MRSA) ; real-time PCR ; health care&ndash ; associated infection ; decolonization therapy ; MDRO control
• 刊名：American Journal of Infection Control
• 出版年：2016
• 出版时间：1 December 2016
• 年：2016
• 卷：44
• 期：12
• 页码：1622-1627
• 全文大小：346 K
• 卷排序：44

文摘

Methicillin-resistant Staphylococcus aureus surveillance with targeted decolonization resulted in a significant 65% decrease in clinical infection. A 2-year project successfully demonstrated that long-term and acute care can work together to lower infections. Decolonization of those with asymptomatic methicillin-resistant Staphylococcus aureus carriage led to reduced nasal carriage prevalence. Mupirocin resistance was reduced during the trial that included determination of decolonization success.