Desymmetrization of ¦Á-diimines: synthesis of new 3-(diaziridin-3-yl)oxaziridines

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• 作者：Emanuele Aresu ; Laura Carroccia ; Stefania Fioravanti ; Lucio Pellacani
• 关键词：Heterocyclic compounds ; Diaziridines ; Oxaziridines ; Regioselectivity
• 刊名：Tetrahedron Letters
• 出版年：2013
• 出版时间：21 August, 2013
• 年：2013
• 卷：54
• 期：34
• 页码：4574-4576
• 全文大小：899 K

文摘

New heterocyclic compounds characterized by the presence of a diaziridine and an oxaziridine ring directly bound were reported. A first desymmetrization reaction of ¦Á-diimines using nosyloxycarbamate as aminating agent in a H₂O/CH₂Cl₂ system gives (E)-3-(iminomethyl)diaziridine-1-carboxylates which were further functionalized obtaining the never synthesized before 3-(diaziridin-3-yl)oxaziridines.