Isochromans from 2-(3′,4′-dihydroxy)phenylethanol

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• 作者：Guiso ; Marcella ; Marra ; Carolina ; Cavarischia ; Claudia
• 关键词：isochromans ; oxa-Pictet&ndash ; Spengler reaction ; hydroxytyrosol
• 刊名：Tetrahedron Letters
• 出版年：2001
• 出版时间：September 10, 2001
• 年：2001
• 卷：42
• 期：37
• 页码：6531-6534
• 全文大小：71.7 K

文摘

A facile method to obtain an isochromanic structure was achieved by the oxa-Pictet–Spengler reaction using 2-(3′,4′-dihydroxy)phenylethanol as starting material. The reaction was performed in very mild conditions on a series of carbonylic compounds. Yields were always satisfactory.