Cognitive function in 1736 participants in NINDS Exploratory Trials in PD Long-term Study-1

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• 作者：Anne-Marie A. Wills^a ; ^{awills@partners.org} ; Jordan J. Elm^b ; Rong Ye^c ; Kelvin L. Chou^d ; Sotirios A. Parashos^e ; Robert A. Hauser^f ; ^g ; Ivan Bodis-Wollner^h ; Vanessa K. Hinsonⁱ ; Chadwick W. Christine^j ; Jay S. Schneider^k ; On behalf of The NINDS NET-PD Investigators
• 关键词：Cognitive impairment ; Parkinson's disease ; SCOPA-COG ; SDMT ; MCI
• 刊名：Parkinsonism & Related Disorders
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：33
• 期：Complete
• 页码：127-133
• 全文大小：392 K
• 卷排序：33

文摘

Cognitive function was measured over 3–6 years in 1741 PD participants. Participants experienced mild decline (−1.9 points over 5 years in the SCOPA-COG). Age, male gender and baseline motor UPDRS were associated with more rapid decline. Self-reported income predicted baseline cognitive function, adjusted for education.