CD105 promotes chondrogenesis of synovium-derived mesenchymal stem cells through Smad2 signaling

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CD105 promotes chondrogenesis of synovium-derived mesenchymal stem cells through Smad2 signaling

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作者：Wenshuai Fan^a ; ¹ ; Jinghuan Li^b ; ¹ ; Yiming Wang^a ; Jianfeng Pan^a ; Shuo Li^a ; Liang Zhu^a ; Changan Guo^a ; ^{changanguo@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Zuoqin Yan^a ; ^{yan1002@hotmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Cartilage repair ; Mesenchymal stem cell ; Chondrogenesis ; CD105 ; Smad signaling
刊名：Biochemical and Biophysical Research Communications
出版年：2016
出版时间：27 May 2016
年：2016
卷：474
期：2
页码：338-344
全文大小：2057 K

文摘

•: Synovium-derived Mesenchymal Stem Cells are heterogeneous for CD105 expression.
•: CD105⁺ SMSCs possess stronger chondrogenic potential.
•: CD105 enhances chondrogenesis through activation of Smad2.

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