Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium

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Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium

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作者：Michael Regn^a ; Bernhard Laggerbauer^a ; Claudia Jentzsch^a ; Deepak Ramanujam^a ; Andrea Ahles^a ; Sonja Sichler^a ; Julia Calzada-Wack^b ; Rory R. Koenen^c ; Attila Braun^d ; Bernhard Nieswandt^d ; Stefan Engelhardt^a ; ^e ; ^{stefan.engelhardt@tum.de" class="auth_mail" title="E-mail the corresponding author}
关键词：Peptidase inhibitor 16 (PI16) ; Chemerin ; RARRES2 ; TIG2 ; Protease inhibition ; Chemerin processing
刊名：Journal of Molecular and Cellular Cardiology
出版年：2016
出版时间：October 2016
年：2016
卷：99
期：Complete
页码：57-64
全文大小：700 K

文摘

•: First evidence for the function of peptidase inhibitor 16
•: PI16 suppresses proteolytic activation of the chemokine chemerin.
•: Generation of globally PI16-deficient mice using a floxed-PI16 allele.

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