Conditional deletion of Eps8 reduces hippocampal synaptic plasticity and impairs cognitive function

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Conditional deletion of Eps8 reduces hippocampal synaptic plasticity and impairs cognitive function

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作者：Yu-Ting Wang^a ; Chiung-Chun Huang^a ; Yun-Shan Lin^a ; Weu-Fang Huang^a ; Cheng-Yi Yang^b ; Cheng-Che Lee^a ; Che-Ming Yeh^a ; Kuei-Sen Hsu^a ; ^b ; ^{richard@mail.ncku.edu.tw" class="auth_mail" title="E-mail the corresponding author}
关键词：Eps8 ; Cognition ; Long-term potentiation ; NMDA receptor ; Hippocampus
刊名：Neuropharmacology
出版年：2017
出版时间：January 2017
年：2017
卷：112
期：part_PA
页码：113-123
全文大小：2303 K

文摘

•: Eps8 deletion results in NMDA receptor hyperfunction.
•: Eps8 deletion promotes decay of long-term potentiation.
•: Eps8 deletion leads to cognitive deficits.

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