The Nrde Pathway Mediates Small-RNA-Directed Histone H3 Lysine 27 Trimethylation in Caenorhabditis elegans

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The Nrde Pathway Mediates Small-RNA-Directed Histone H3 Lysine 27 Trimethylation in Caenorhabditis elegans

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作者：Hui Mao¹ ; ² ; Chengming Zhu¹ ; ² ; Dandan Zong¹ ; Chenchun Weng¹ ; Xiangwei Yang¹ ; Hui Huang¹ ; Dun Liu¹ ; Xuezhu Feng¹ ; ^{fengxz@ustc.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Shouhong Guang¹ ; ^{sguang@ustc.edu.cn" class="auth_mail" title="E-mail the corresponding author}
刊名：Current Biology
出版年：2015
出版时间：21 September 2015
年：2015
卷：25
期：18
页码：2398-2403
全文大小：1045 K

文摘

•: Exo-RNAi induces H3K27me3 at targeted loci, a process depending on the Nrde pathway
•: Endo-siRNA elicits H3K27me3 through the Nrde pathway
•: Exo-RNAi-induced H3K27me3 is maintained for several generations
•: RNAi-directed H3K9me3 and H3K27me3 have distinct genetic requirements

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