Effects of zinc oxide nanoparticles on human coronary artery endothelial cells

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Effects of zinc oxide nanoparticles on human coronary artery endothelial cells

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作者：Kai-Jen Chuang^a ; ^b ; ¹ ; ^{kjc@tmu.edu.tw" class="auth_mail" title="E-mail the corresponding author} ; Kang-Yun Lee^c ; ^d ; ¹ ; ^{kangyunlee68@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Chih-Hong Pan^e ; ^f ; ^{chpan@mail.iosh.gov.tw" class="auth_mail" title="E-mail the corresponding author} ; Ching-Huang Lai^f ; ^{lgh@ndmctsgh.edu.tw" class="auth_mail" title="E-mail the corresponding author} ; Lian-Yu Lin^g ; ^{hspenos@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author} ; Shu-Chuan Ho^c ; ^h ; ^{shu-chuan@tmu.edu.tw" class="auth_mail" title="E-mail the corresponding author} ; Kin-Fai Hoⁱ ; ^j ; ^{kfho@cuhk.edu.hk" class="auth_mail" title="E-mail the corresponding author} ; Hsiao-Chi Chuang^c ; ^h ; ^{r92841005@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author}
关键词：AGTR1 ; Inflammation ; Nanoparticles ; Nitric oxide ; Oxidative stress
刊名：Food and Chemical Toxicology
出版年：2016
出版时间：July 2016
年：2016
卷：93
期：Complete
页码：138-144
全文大小：1315 K

文摘

•: Effects of ZnONP were determined in HCEAC.
•: Alteration in 8-OHdG, IL-6 and NO occurred by ZnONPs.
•: AGTR1 is an important gene in response to ZnONP exposure.
•: Calcium signalling pathway is important after ZnONPs exposure.
•: ZnONP is associated with coronary artery endothelial cell dysfunction.

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