Serotonin modulates response properties of neurons in the dorsal cochlear nucleus of the mouse

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• 作者：Richard A. Felix II ; ^{rfelix@wsu.edu} ; Cameron J. Elde ; Alexander A. Nevue ; Christine V. Portfors
• 关键词：Auditory brainstem ; 5-HT ; DCN ; Fusiform cell ; Neuromodulation
• 刊名：Hearing Research
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：344
• 期：Complete
• 页码：13-23
• 全文大小：1764 K
• 卷排序：344

文摘

The dorsal cochlear nucleus (DCN) of the mouse contains dense innervation from serotonergic fibers. Application of serotonin has heterogeneous effects on sound-evoked response properties of DCN neurons, but primarily acts to increase excitability. Increased excitability of DCN neurons is largely mediated by the 5-HT2 receptor.