Worsening Renal Function during Management for Chronic Heart Failure with Reduced Ejection Fraction: Results From the Pro-BNP Outpatient Tailored Chronic Heart Failure Therapy (PROTECT) Study

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• 作者：Nasrien E. Ibrahim ; MD¹ ; ² ; Hanna K. Gaggin ; MD ; MPH¹ ; ² ; Dustin J. Rabideau ; MS³ ; Parul U. Gandhi ; MD⁴ ; Aditi Mallick ; MD¹ ; James L. Januzzi Jr. ; MD¹ ; ² ; ^{jjanuzzi@partners.org}
• 关键词：Heart failure ; biomarkers ; renal failure
• 刊名：Journal of Cardiac Failure
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：23
• 期：2
• 页码：121-130
• 全文大小：624 K
• 卷排序：23

文摘

Worsening renal failure (WRF) is common in the management of chronic heart failure. WRF is not associated with outcome and should not deter clinicians from maximizing guideline-directed medical therapy. N-terminal pro-B type natriuretic peptide (NT-proBNP)-guided care was not associated with more WRF compared with standard of care. NT-proBNP-guided care was not associated with worse outcomes.