The solubility of pronamide in five typical solvents was determined by a dynamic equilibrium method.
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The experimental solubility data were correlated by the Apelblat equation with a good fitting result.
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The pronamide dissolving process in each solvent involved was endothermic, entropy-driven and non-spontaneous.
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The main contributor to dissolving Gibbs free energy of pronamide was enthalpy.
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