An investigation of the potential for epigenetic inactivation by transcription read-through in a sporadic colorectal cancer

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An investigation of the potential for epigenetic inactivation by transcription read-through in a sporadic colorectal cancer

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作者：Sameer Srivastava^a ; ^b ; ^{sameers@mnnit.ac.in" class="auth_mail" title="E-mail the corresponding author} ; Anne K. Ludwig^a ; ^c ; Jason W.H. Wong^a ; Luke B. Hesson^a
关键词：CGH ; Comparative Genomic Hybridization ; CRC ; Colo-Rectal Cancer ; CNV ; Copy Number Alteration ; TRT ; Transcriptional Read Through ; TSG ; Tumor Suppressor Gene
刊名：Gene
出版年：2016
出版时间：1 July 2016
年：2016
卷：585
期：1
页码：154-158
全文大小：1069 K

文摘

•: Identified deletions in a CRC using CGH
•: Identified 6 loci vulnerable to Transcriptional Read Through (TRT)
•: TRT could be a rare phenomenon for epigenetic inactivation in sporadic CRCs.

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