Porcupine-dependent Wnt signaling controls stromal proliferation and endometrial gland maintenance through the action of distinct WNTs

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Porcupine-dependent Wnt signaling controls stromal proliferation and endometrial gland maintenance through the action of distinct WNTs

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作者：Omar Farah^a ; ^b ; Steffen Biechele^d ; Janet Rossant^e ; ^f ; Daniel Dufort^a ; ^b ; ^c ; ^{Daniel.dufort@mcgill.ca}
关键词：FGF ; Fibroblast growth factor ; GE ; Glandular epithelium ; Ihh ; Indian hedgehog ; LE ; Luminal epithelium ; LIF ; Leukemia Inhibitory Factor ; MBOAT ; Membrane bound o-acyl transferase ; P4 ; Progesterone ; PgrCre/+ ; Progesterone receptor-Cre ; PND ; Post natal day ; Porcn ; Porcupine homolog ; PorcnΔ/Δ ; Porcupine Conditional knockout ; Porcnfloxed/floxed ; Porcupine floxed control ; SMA ; Smooth muscle actin
刊名：Developmental Biology
出版年：2017
出版时间：1 February 2017
年：2017
卷：422
期：1
页码：58-69
全文大小：2969 K
卷排序：422

文摘

Porcupine-dependent Wnts are not required for post-natal gland development. Wnt7a is required endometrial gland formation. Wnt5a is necessary for stromal cell proliferation.