Comparison of the chemical consituents and immunomodulatory activity of ophiopogonis radix from two different producing areas

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• 作者：Xiaoyan Lu^a ; Wei Tong^a ; Shufang Wang^a ; Jinghui Li^b ; Jie Zheng^a ; Xiaohui Fan^a ; ^{fanxh@zju.edu.cn} ; Li Liu^b ; ^{boltliu@163.com}
• 关键词：Ophiopogonis radix ; Zhemaidong (ZMD) ; Chuanmaidong (CMD) ; Characteristic constituents ; Immunomodulatory activity ; Zebrafish
• 刊名：Journal of Pharmaceutical and Biomedical Analysis
• 出版年：2017
• 出版时间：5 February 2017
• 年：2017
• 卷：134
• 期：Complete
• 页码：60-70
• 全文大小：2276 K
• 卷排序：134

文摘

Chemical profiles of Ophiopogonis Radix from two areas were compared by LC–MS. 19 constituents were identified as chemical markers to distinguish ZMD from CMD. ZMD possesses better immunomodulatory activities than CMD in zebrafish. Geographical area should be considered in preparing herb medicine.