Found in translation: Understanding the biology and behavior of experimental traumatic brain injury

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Found in translation: Understanding the biology and behavior of experimental traumatic brain injury

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作者：Corina O. Bondi^a ; ^b ; ^c ; ^d ; Bridgette D. Semple^j ; ^k ; Linda J. Noble-Haeusslein^j ; Nicole D. Osier^b ; ^g ; Shaun W. Carlson^b ; ^h ; C. Edward Dixon^b ; ^c ; ^h ; ⁱ ; Christopher C. Giza^l ; ^m ; Anthony E. Kline^a ; ^b ; ^c ; ^d ; ^e ; ^f ; ^{klineae@upmc.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：AST ; attentional set-shifting test ; bTBI ; blast traumatic brain injury ; BDNF ; brain-derived neurotrophic factor ; CCI ; controlled cortical impact ; CD ; compound discrimination ; CFC ; contextual fear conditioning ; ChAT ; choline acetyltransferase ; Cr ; creatine ; CTE ; chronic traumatic encephalopathy ; DA ; dopamine ; DAT ; dopamine transporter ; DTI ; diffusion tensor imaging ; ED ; extradimensional ; EE ; environmental enrichment ; FP ; fluid percussion ; ID ; intradimensional ; MWM ; Morris water maze ; NAA ; N-acety
刊名：Neuroscience & Biobehavioral Reviews
出版年：2015
出版时间：November 2015
年：2015
卷：58
期：Complete
页码：123-146
全文大小：3301 K

文摘

•: In vivo TBI models provide essential understanding of mechanisms and recovery.
•: Multiple deficits in social behavior can be detected after TBI in young rodents.
•: The AST is a sensitive measure of executive function after experimental TBI.
•: Environmental enrichment is a preclinical model of neurorehabilitation.
•: No single test exists to diagnose concussion accurately.

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