Exogenous insulin-like growth factor 2 administration enhances memory consolidation and persistence in a time-dependent manner

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Exogenous insulin-like growth factor 2 administration enhances memory consolidation and persistence in a time-dependent manner

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作者：Younghwan Lee^a ; ^c ; ¹ ; Young Woo Lee^a ; ^c ; ¹ ; Qingtao Gao^a ; ^c ; Younghwa Lee^a ; ^c ; Hyung Eun Lee^a ; ^c ; Jong Hoon Ryu^a ; ^b ; ^c ; ^{jhryu63@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author}
关键词：Arc ; activity-regulated cytoskeleton-associated protein ; IGF1R ; insulin-like growth factor 1 receptor ; IGF2 ; insulin-like growth factor 2 ; IGF2R ; insulin-like growth factor 2 receptor ; LTM ; long-term memory ; mBDNF ; mature brain-derived neurotrophic factor ; ANOVA ; one-way analysis of variance ; PBS ; phosphate-buffered saline
刊名：Brain Research
出版年：2015
出版时间：5 October 2015
年：2015
卷：1622
期：Complete
页码：466-473
全文大小：754 K

文摘

class="label">•: Hippocampal IGF2 injection within 9 h after training enhances memory consolidation.
class="label">•: Hippocampal IGF2 injection at 12 h after training enhances memory persistence.
class="label">•: Hippocampal IGF2 regulates memory consolidation or persistence via IGF2 receptor.

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