Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property

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Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property

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作者：Hyung Eun Lee^a ; ^c ; Se Jin Jeon^a ; ^c ; Byeol Ryu^a ; ^c ; Se Jin Park^a ; ^c ; Sang Yoon Ko^a ; ^c ; Younghwan Lee^a ; ^c ; Eunji Kim^a ; ^c ; Sunhee Lee^a ; ^c ; Haneul Kim^a ; ^c ; Dae Sik Jang^a ; ^c ; ^{dsjang@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Jong Hoon Ryu^a ; ^b ; ^c ; ^{jhryu63@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author}
关键词：Swertisin ; Memory impairment ; Adenosine ; Alzheimer&rsquo ; s disease
刊名：Behavioural Brain Research
出版年：2016
出版时间：1 June 2016
年：2016
卷：306
期：Complete
页码：137-145
全文大小：1555 K

文摘

class="label">•: Swertisin is effective in memory improvement both in normal and impairment model.
class="label">•: Ameliorating effect of swertisin is from adenosine A1 receptor antagonistic property.
class="label">•: Swertisin increased the phosphorylation levels of PKA and CREB.

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