Potential of boron neutron capture therapy (BNCT) for malignant peripheral nerve sheath tumors (MPNST)

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Potential of boron neutron capture therapy (BNCT) for malignant peripheral nerve sheath tumors (MPNST)

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作者：Takuya Fujimoto^a ; ^{fujitaku@hp.pref.hyogo.jp" class="auth_mail" title="E-mail the corresponding author} ; Tooru Andoh^b ; Tamotsu Sudo^c ; Ikuo Fujita^a ; Naomasa Fukase^a ; Tamotsu Takeuchi^d ; Hiroshi Sonobe^e ; Masayoshi Inoue^f ; Tkanori Hirose^g ; Toshiko Sakuma^g ; Hiroshi Moritake^h ; Tohru Sugimotoⁱ ; Teruya Kawamoto^j ; Yoshinobu Fukumori^b ; Satomi Yamamoto^k ; Shinji Atagi^l ; Yoshinori Sakurai^m ; Masahiro Kurosaka^j ; Koji Onoⁿ ; Hideki Ichikawa^b ; Minoru Suzukiⁿ
关键词：Malignant peripheral nerve sheath tumors (MPNST) ; NF1 ; Clear cell sarcoma ; HS-Sch-2 ; Boron neutron capture therapy (BNCT) ; p-Borono-L-phenylalanine
刊名：Applied Radiation and Isotopes
出版年：2015
出版时间：December 2015
年：2015
卷：106
期：Complete
页码：220-225
全文大小：1529 K

文摘

class="label">•: MPNST responds to no effective treatment method other than surgery.
class="label">•: Two clinical cases of MPNST demonstrated the efficacy of BNCT.
class="label">•: MPNST cells and the MPNST-bearing animal model showed high uptake of boron.
class="label">•: The results demonstrated the efficacy of BNCT for MPNST.

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