Augmenter of liver regeneration (ALR) restrains concanavalin A-induced hepatitis in mice

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Augmenter of liver regeneration (ALR) restrains concanavalin A-induced hepatitis in mice

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作者：Mao Mu^a ; ^b ; ^{mumao0102@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Zhenwei Zhang^b ; ^{zhengwei-523@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Yi Cheng^a ; ^b ; ^{chengyidyt@163.com" class="auth_mail" title="E-mail the corresponding author} ; Guangze Liu^b ; ^{lgze68@163.com" class="auth_mail" title="E-mail the corresponding author} ; Xiusheng Chen^b ; ^{13631341977@163.com" class="auth_mail" title="E-mail the corresponding author} ; Xin Wu^a ; ^{wuxin44771@163.com" class="auth_mail" title="E-mail the corresponding author} ; Caifang Zhuang^b ; ^{1003550116@qq.com" class="auth_mail" title="E-mail the corresponding author} ; Bingying Liu^a ; ^{liubingying530@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Xiangping Kong^b ; ^{xiangping_kong@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Song You^a ; ^{yousong207@163.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Augmenter of liver regeneration ; Concanavalin A ; Hepatitis ; T cell activation ; MAPK ; NF-κB
刊名：International Immunopharmacology
出版年：2016
出版时间：June 2016
年：2016
卷：35
期：Complete
页码：280-286
全文大小：950 K

文摘

class="label">•: ALR restrains hepatitis via inhibiting of CD4⁺, CD8⁺ T cells infiltration.
class="label">•: ALR reduces the secretion of pro-inflammatory cytokines and chemokines.
class="label">•: ALR inhibits the activation of JNK, MAP kinase and NF-κB pathways in the hepatitis.
class="label">•: ALR displays an extraordinary immunoregulatory effect.

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