G-quadruplex DNA interactions, docking and cell photocytotoxicity research of porphyrin dyes

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G-quadruplex DNA interactions, docking and cell photocytotoxicity research of porphyrin dyes

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作者：Ping Zhao^a ; ^{zhaoping666@163.com" class="auth_mail" title="E-mail the corresponding author} ; Min-Chao Liu^a ; Min Zheng^b ; ^{sourcabage@126.com" class="auth_mail" title="E-mail the corresponding author} ; Shu-fang Jin^a ; Ding-tong Tang^a ; Jiong Chen^a ; Yan-na Ma^a ; Jia-qi Lin^a ; Xia-hong Wang^a ; Hong-jian Liu^a
关键词：Cationic porphyrins ; G-quadruplex DNA ; Spectral method ; Molecular dock ; Steric hindrance ; Photocytotoxicity
刊名：Dyes and Pigments
出版年：2016
出版时间：May 2016
年：2016
卷：128
期：Complete
页码：41-48
全文大小：1608 K

文摘

class="label">•: Novel expanded cationic porphyrin was successfully designed and synthesized.
class="label">•: Spectral and Docking results show TPMPyP₂ is more favorable in G4-DNA binding.
class="label">•: TPMPyP₂ is more potential as photochemotherapeutic agents.

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