Novel silver(I)- and gold(I)-N-heterocyclic carbene complexes. Synthesis, characterization and evaluation of biological activity against tumor cells

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Novel silver(I)- and gold(I)-N-heterocyclic carbene complexes. Synthesis, characterization and evaluation of biological activity against tumor cells

详细信息查看全文

作者：Oriel Sanchez^a ; ^b ; Sorenlis Gonzá ; lez^b ; Mercedes Ferná ; ndez^c ; Angel R. Higuera-Padilla^b ; Yokoy Leon^b ; David Coll^b ; Alba Vidal^b ; Peter Taylor^c ; Izaskun Urdanibia^c ; Marí ; a Cristina Goite^b ; ^{hamarkeys@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; William Castro^b ; ^{wcastro10@gmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：N-heterocyclic carbene ; Metal&ndash ; NCH complexes ; DNA ; Lipophilicity ; Cytostatic ; Cytotoxic
刊名：Inorganica Chimica Acta
出版年：2015
出版时间：1 October 2015
年：2015
卷：437
期：Complete
页码：143-151
全文大小：1951 K

文摘

class="label">•: Ag₂(渭-魏²C,C′-C₁₀H₁₄N₄)Br₂ and Au₂(渭-魏²C,C′-C₁₀H₁₄N₄)Cl₂ have been synthesized and characterized.
class="label">•: Interactions of complexes with calf thymus CT-DNA have been verified.
class="label">•: The gold complex is more lipophilic than the silver complex.
class="label">•: Au₂(渭-魏²C,C′-C₁₀H₁₄N₄)Cl₂ shows good biological activity against PC3 and HT29 tumor cell lines.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.