Inhibition of precancerous lesions development in kidneys by chrysin via regulating hyperproliferation, inflammation and apoptosis at pre clinical stage

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Inhibition of precancerous lesions development in kidneys by chrysin via regulating hyperproliferation, inflammation and apoptosis at pre clinical stage

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作者：Summya Rashid ; Sana Nafees ; Abul Vafa ; Shekh Muhammad Afzal ; Nemat Ali ; Muneeb U. Rehman ; Syed Kazim Hasan ; Aisha Siddiqi ; Preeti Barnwal ; Ferial Majed ; Sarwat Sultana ; ^{sarwat786@rediffmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Renal cell carcinoma ; Chrysin ; ROS ; Inflammation ; Apoptosis ; Hyper proliferation
刊名：Archives of Biochemistry and Biophysics
出版年：2016
出版时间：15 September 2016
年：2016
卷：606
期：Complete
页码：1-9
全文大小：2595 K

文摘

class="label">•: Up regulation of inflammatory marker proteins-mechanism behind renal cancer.
class="label">•: Increase in tumor incidences and proliferation-mechanism behind renal cancer.
class="label">•: Down regulation of anti-oxidant armory and apoptosis-mechanism behind renal cancer.
class="label">•: Damage in normal histological and cellular architecture.
class="label">•: Chrysin attenuates renal carcinogenesis by modulation of above molecular pathways.