The impact of BMI on early colorectal neoplastic lesions and the role of endoscopic diagnosis:. An Italian observational study
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文摘
CRC often arises from polyps: an early detection and resection are effective in decreasing both incidence and mortality rate. Relation between risk factors, adenomas and CRC have been showed, but there is little evidence for overweight association with preneoplastic lesions. This study analyzed the correlation between body mass index (BMI) and primitive site of polyps.

Methods

We performed a retrospective study, in a period between January 2010 and October 2014. Subjects aged 50 years and older who underwent their first-time screening colonoscopy were included. Reports regarding characteristic of the polyps were collected.

Results

142 patients were enrolled and they were divided into two groups: group I – patients with left sided colonic polyps, and group II – patients who right sided colonic polyps. The ANOVA test-one way, documents a difference between the BMI and the colon localization of polyps.

Conclusions

Patients with overweight had a higher risk to develop lesions in the left colon compared to patients with normal weight. Despite the fact that Italian epidemiological studies have found a prevalence of polyps of 44–53% in rectal-sigmoid segment, 32–36% in transverse segment and of 14–20% in right segment, we showed an incidence of 26.05% for right sided polyps, which maybe related with the eating habits of the territory.

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