Frozen section evaluation of margins in radical prostatectomy specimens: a contemporary study and literature review

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Frozen section evaluation of margins in radical prostatectomy specimens: a contemporary study and literature review

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作者：Amberly L. Nunez ; M.D.^a ; ¹ ; ^{amberly.nunez@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Giovanna A. Giannico ; M.D.^b ; ^{giovanna.giannico@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author} ; Faisal Mukhtar ; M.D.^a ; ² ; ^{fmukhtar@ufl.edu" class="auth_mail" title="E-mail the corresponding author} ; Virginia Dailey ; M.D.^a ; ³ ; ^{virginialeedailey@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Rizk El-Galley ; M.D.^c ; ⁴ ; ^{relgall50@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Omar Hameed ; M.D.^b ; ^{omar.hameed@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：Frozen section ; Prostate cancer ; Positive surgical margin ; Radical prostatectomy ; Biochemical recurrence
刊名：Annals of Diagnostic Pathology
出版年：2016
出版时间：October 2016
年：2016
卷：24
期：Complete
页码：11-18
全文大小：4630 K

文摘

class="label">•: We investigated the use of frozen sections (FSs) at radical prostatectomy (RP).
class="label">•: Sensitivity and specificity were 85% and 100% for diagnosis of adenocarcinoma.
class="label">•: Positive FS was associated with perineural invasion on biopsy and higher stage at RP.
class="label">•: Accuracy of FS in predicting the overall prostatectomy final margin status was 81%.
class="label">•: We suggest that FS has limited, if any predictive utility, for final margin status.

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