Developmental regulation of hippocampal long-term depression by cofilin-mediated actin reorganization

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Developmental regulation of hippocampal long-term depression by cofilin-mediated actin reorganization

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作者：Feng Cao^a ; ^b ; ^d ; ¹ ; Zikai Zhou^a ; ^d ; ^e ; ¹ ; Xingxiu Pan^d ; Celeste Leung^a ; ^b ; Wei Xie^d ; ^e ; Graham Collingridge^b ; ^c ; ^f ; Zhengping Jia^a ; ^b ; ^{zhengping.jia@sickkids.ca" class="auth_mail" title="E-mail the corresponding author}
关键词：Hippocampal LTD ; AMPA receptor ; NSF ; PICK1 ; Actin ; Cofilin ; Developmental regulation
刊名：Neuropharmacology
出版年：2017
出版时间：January 2017
年：2017
卷：112
期：part_PA
页码：66-75
全文大小：3036 K

文摘

class="label">•: The protein level and activity of cofilin are developmentally regulated.
class="label">•: Hippocampal LTD requires cofilin in mature but not in young mice.
class="label">•: Hippocampal LTD requires GluA2 interactions with NSF and PICK1 in both young and mature mice.

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