Separate batches of neurons were used to investigate the effect of the differentiation process on gene expression and sensitivity to drugs

No significant batch effect were observed in gene expression, cytosine modification levels or neuronal sensitivity to chemotherapeutic agents

Genes involved in neuropathy had relatively higher expression levels in these samples across different time points than expected by chance

Data supports using iPSC derived neurons for studies of human neuropathy and , druggable targets to prevent neuropathy