Inflammatory cytokines provide both infection-responsive and developmental signals for blood development: Lessons from the zebrafish

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Inflammatory cytokines provide both infection-responsive and developmental signals for blood development: Lessons from the zebrafish

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作者：Chris Hall ; ^{c.hall@auckland.ac.nz" class="auth_mail" title="E-mail the corresponding author} ; Phil Crosier ; Kathryn Crosier
关键词：Zebrafish ; Hematopoiesis ; Inflammation ; Cytokines ; Demand-driven hematopoiesis ; Infection
刊名：Molecular Immunology
出版年：2016
出版时间：January 2016
年：2016
卷：69
期：Complete
页码：113-122
全文大小：1830 K

文摘

•: Inflammatory signaling pathways influence HSC function during infection.
•: Sterile inflammatory signaling pathways help orchestrate HSC production within the embryo.
•: The zebrafish model is ideally suited to investigate inflammatory processes and HSC biology.
•: Research using the zebrafish has uncovered new mechanistic insight into how inflammatory signaling pathways influence the HSC compartment.

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