Clinical settings in knee osteoarthritis: Pathophysiology guides treatment

详细信息    查看全文

• 作者：Gabriel Herrero-Beaumont^a ; ^{gherrero@fjd.es} ; Jorge A. Roman-Blas^a ; Olivier Bruyè ; re^b ; Cyrus Cooper^c ; ^d ; John Kanis^e ; Stefania Maggi^f ; René ; Rizzoli^g ; Jean-Yves Reginster^h
• 关键词：Osteoarthritis ; Phenotypes ; Etiopathogenesis ; Clinical manifestations ; Treatment
• 刊名：Maturitas
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：96
• 期：Complete
• 页码：54-57
• 全文大小：534 K
• 卷排序：96

文摘

Osteoarthritisis the most common chronic joint disorder and its prevalence increases rapidly during midlife. The complex nature of the relationships between numerous factors involved in the etiopathogenesis makes difficult the identification of osteoarthritisis phenotypes. An adequate stratification of patients with osteoarthritisis into particular phenotypes could optimize the design of individualized treatments. Four well-defined clinical phenotypes are proposed in osteoarthritisis: biomechanical, osteoporotic, metabolic and inflammatory.