Fronto-striatal glutamate in children with Tourette's disorder and attention-deficit/hyperactivity disorder

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• 作者：Jilly Naaijen^a ; ¹ ; ^{j.naaijen@donders.ru.nl} ; Natalie J. Forde^a ; ^b ; ¹ ; David J. Lythgoe^c ; Sophie E.A. Akkermans^a ; Thaira J.C. Openneer^b ; Andrea Dietrich^b ; Marcel P. Zwiers^a ; Pieter J. Hoekstra^b ; ² ; Jan K. Buitelaar^a ; ^d ; ²
• 关键词：Tourette syndrome ; ADHD ; Glutamate ; Fronto-striatal circuit ; MRS
• 刊名：NeuroImage: Clinical
• 出版年：2017
• 出版时间：2017
• 年：2017
• 卷：13
• 期：Complete
• 页码：16-23
• 全文大小：743 K
• 卷排序：13

文摘

Large pediatric sample of ADHD and TD participants 3 Tesla proton MRS utilized to investigate fronto-striatal glutamate concentrations No differences in glutamate concentrations in the disorder groups compared with controls ACC glutamate concentrations associated with obsessive–compulsive symptoms in TD