Characterization of CTX-M enzymes, quinolone resistance determinants, and antimicrobial residues from hospital sewage, wastewater treatment plant, and river water

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• 作者：Danieli Conte^a ; ¹ ; ^{conte.danieli@gmail.com} ; Jussara Kasuko Palmeiro^a ; ^b ; ² ; ^{jukasuko@gmail.com} ; Keite da Silva Nogueira^c ; ² ; ^{keitenogueira@gmail.com} ; Thiago Marenda Rosa de Lima^d ; ³ ; ^{thiagomrl@sanepar.com.br} ; Marco André ; Cardoso^a ; ^e ; ¹ ; ^{marcoacardoso@yahoo.com.br} ; Roberto Pontarolo^e ; ⁴ ; ^{pontarolo@ufpr.br} ; Flá ; via Lada Degaut Pontes^e ; ⁴ ; ^{flaviadegaut@yahoo.com.br} ; Libera Maria Dalla-Costa^a ; ^b ; ^{lmdallacosta@gmail.com}
• 关键词：CDT ; combined disc test ; DD ; disc diffusion ; DRW ; downstream river water ; ERIC ; enterobacterial repetitive intergenic consensus sequence ; ESBL ; extended-spectrum β-lactamase ; FQ ; fluoroquinolone ; LC-MS/MS ; liquid chromatography coupled with tandem mass spectrometry ; MALDI-TOF ; matrix-assisted laser desorption ionization time-of-flight mass spectrometry ; MDR ; multidrug-resistant ; MIC ; minimum inhibitory concentration ; PMQR ; plasmid-mediated quinolone resistance ; QRDR ; quinolone resistance-determi
• 刊名：Ecotoxicology and Environmental Safety
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：136
• 期：Complete
• 页码：62-69
• 全文大小：515 K
• 卷排序：136

文摘

β-lactamase-producing bacteria and quinolone resistance are found in both raw and treated water. CTX-M is the prevalent β-lactamase among isolated resistant bacteria. GES-5 carbapenemase is found in hospital effluent. Sewage treatment does not efficiently remove multidrug-resistant bacteria.