A potentiometric biosensor is developed for direct serological diagnosis of Bovine Respiratory Disease (BRD).
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The sensor is based on extended-gate field-effect transistors.
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A major pathogen of BRD, Bovine Herpes Virus-1 (BHV-1), is used as a model system.
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The sensor performance is equivalent to Surface Plasmon Resonance (SPR) and ELISA.
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The FET sensor is significantly faster than ELISA (<10 min).
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