Thirty years with cyclodextrins

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• 作者：Dominique Duchê ; ne ; ^{dominique.duchene@u-psud.fr" class="auth_mail" title="E-mail the corresponding author} ; Amé ; lie Bochot
• 关键词：CDs ; cyclodextrins ; DMPC ; dimyristoylphosphatidylcholine ; DPPA ; dipalmitoylphosphatidic acid ; DPPC ; dipalmitoylphosphatidylcholine ; DSC ; differential scanning calorimetry ; Et-β-CD ; ethyl-β-CD ; HP-β-CD ; hydroxypropyl-β-CD ; IM ; indomethacin ; IR ; infrared ; ITC ; isothermal titration microcalorimetry ; Me-β-CD ; methyl-β-CD ; MD ; modified dextran ; MOF ; metal-organic frameworks ; NMR ; nuclear magnetic resonance ; PACA ; poly(alkylcyanoacrylates) ; pβ-CD ; polyβ-CD ; PBLG ; poly(γ-benzyl-l-glutamate) ; PIBCA ; pol
• 刊名：International Journal of Pharmaceutics
• 出版年：2016
• 出版时间：30 November 2016
• 年：2016
• 卷：514
• 期：1
• 页码：58-72
• 全文大小：1077 K

文摘

This paper reviews the work carried out on cyclodextrins during some thirty years at the Institut Galien Paris-Sud, UMR CNRS 8612, Université Paris-Sud. It represents the normal evolution of this domain of science and the numerous possibilities of cyclodextrins for being a tool adaptable to the most complex situations. The works which have been carried out concern: the investigation of general characteristics of cyclodextrins and derivatives, the preparation and evaluation of inclusion complexes, the use of cyclodextrins in the preparation of drug delivery systems, the various possibilities offered by cyclodextrins and their derivatives for nanoparticle preparation and finally the use of cyclodextrins for the preparation of biomaterials is evoked.