Synthesis and use of penicillamine-coated gold nanoparticles to enhance the optical rotation signal of menthone enantiomers.

A new designed home-made sample-cell to assure the reproducibility of solutions containing coated nanoparticles were used to produce the maximum ellipticity between menthone enantiomers by measuring the circular dichroism signal.

Enantioselective discrimination of menthone enantiomers by using the synthesised coated nanoparticles for the determination of the enantiomeric excess.

Analytical determination of these compounds in peppermint oil by the developed method avoiding the use of chiral HPLC separation.