Physicochemical characterization of lauryl glycinate-dodecyl sulfate equimolar complex: A base-triggerable catanionic liposomal system

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• 作者：S. Thirupathi Reddy ; D. Sivaramakrishna ; Musti J. Swamy ; ^{mjswamy1@gmail.com} ; ^{mjswamy@uohyd.ac.in}
• 关键词：CMC ; critical micellar concentration ; DSC ; differential scanning calorimetry ; ΔGb ; free energy of binding ; ΔHb ; enthalpy of binding ; ITC ; isothermal titration calorimetry ; Kb ; binding (association) constant ; LG· ; HCl ; lauryl glycinate hydrochloride ; LUVs ; large unilamellar vesicles ; OLEA ; O-lauroylethanolamine ; PXRD ; powder X-ray diffraction ; ΔSb ; entropy of binding ; SDS ; sodium dodecyl sulfate ; Tt ; transition temperature ; TEM ; transmission electron microscopy
• 刊名：Colloids and Surfaces A: Physicochemical and Engineering Aspects
• 出版年：2017
• 出版时间：5 March 2017
• 年：2017
• 卷：516
• 期：Complete
• 页码：139-146
• 全文大小：1801 K
• 卷排序：516

文摘

Lauryl glycinate (LG) and dodecyl sulfate (DS) form an equimolar catanionic complex. The equimolar LG-DS complex assembles to give spherical unilamellar liposomes. The LG-DS catanionic liposomes are base labile and undergo disruption at pH > 8.0. The LG-DS liposomes can be used to develop base-triggerable drug delivery systems.